REINVENT with Quantum Chemistry Calculations
May 30, 2023 ยท View on GitHub
This repository includes:
- REINVENT and related packages in
./REINVENTand./pkgs - Initial ChEMBL prior network in
./data - Calibration set along with TD-DFT results and references in
./calibration - Results for generated molecules in
./results - Scripts for setting up configurations and starting training for REINVENT in
./run
Installation
Note: The part of source codes related to job management and data parsing may need to be modified to fit your own system.
- Clone this GitHub repo
- Create a conda environment with reinvent.yml
$ conda env create -f reinvent.yml
Requirements
- SCScore: Synthetic complexity score prediction model
- AiZynthFinder: Retrosynthetic planning tool
Acknowledgments
- REINVENT 3.2: REINVENT model
- ReinventCommunity: Useful tutorials for REINVENT in jupyter notebooks