Supported Models

July 16, 2026 · View on GitHub

OpenDDE currently exposes one public model:

Model nameMSA / Constraint / RNA MSA / TemplateModel Parameters (M)Data cutoff
opendde_v1✓ / × / ✓ / ✓6562021-09-30

Exact parameter count: 655,791,538, rounded to 656 M. opendde_v1 uses the defaults in opendde/config/model_base.py.

Use it with:

opendde pred -i examples/input.json -o ./output -n opendde_v1

Checkpoint path by default:

$OPENDDE_ROOT_DIR/checkpoint/opendde.pt

Released Checkpoints

CheckpointUse caseDownload
opendde.ptGeneral-purpose OpenDDE checkpoint.opendde.pt
opendde_abag.ptABAG-optimized checkpoint for antibody-antigen complexes.opendde_abag.pt

The release source revision is eddd563ce96571f784012edd8f045181c8f8627d. Exact checkpoint sizes and SHA-256 digests are recorded in the package-installed opendde/config/model_manifest.json:

CheckpointSize (bytes)SHA-256
opendde.pt2,625,249,0697b826620390afad877ee2babc6a4d0df81b94d3a0be030959853d6a7da0807cc
opendde_abag.pt2,625,271,5095cf37441ddef2a2f148b81dd4a218ad274f996fecaf17dec901ab6cf1351713d

opendde.pt is the default checkpoint for -n opendde_v1. Keep the ABAG-optimized checkpoint as opendde_abag.pt and pass it explicitly with --load_checkpoint_path.

Recommended inference defaults:

  • model.N_cycle = 10
  • sample_diffusion.N_step = 200
  • triangle kernels: auto

These are also the current opendde pred CLI defaults for opendde_v1.

Legacy constraint fields are ignored by the inference-only build. Use covalent_bonds for supported covalent links.