Jrihon

April 23, 2025 · View on GitHub

Software engineer over at BioLizard (Ghent, Belgium).

Did my PhD (Medicinal Chemistry, KU Leuven, Rega Institute) on the topic of synthetic nucleic acids, using computational chemistry and cheminformatics. I developed forcefields and modelled bespoke xenobiotic nucleic acids, which was facilitated by the Ducque (model builder) and pucke.rs (conformational sampling) tools I created during my research projects.

Feel free to reach out to me on my research and future endeavours!

Programming

Languages

Python | Rust | Bash | Typst | LaTeX | Lua | Julia | Nextflow

Brief encounters with C | Pascal

Check out my projects !

  • jrihon/Ducque - A model builder to generate models of XNA, with user-implementable analogs, in Python!
  • jrihon/puckepy - Python module for QM-based conformational sampling of molecules - written in Rust btw.
  • jrihon/puckers - Rust CLI for QM-based conformational sampling of molecules.
  • jrihon/mutineer.lua - Extensible commenting plugin for nvim, in Lua.
  • jrihon/multi-bibs - Support multiple bibliographies e.g. for thesis manuscripts, in Typst.

I use the kitty terminal emulator and have my prompts customised through starship. To work and manage projects, I use tmux. All my programming and general text editing is done with neovim.

PhD research

  • Modeling the behaviour of synthetic analogs of DNA and RNA (XNA).
  • Perform predictions using pure in silico methodologies.
  • Use computational chemistry to describe the modified analogs (QM |force field design | MM).
  • Developed cheminformatics tools to design a pipeline for model prediction (programming).

SPOILER ALERT --- GREAT SUCCESS !

Tags

computational chemisty | cheminformatics | molecular dynamics | quantum mechanics | molecular mechanics | python | rust | synthetic nucleic acids | XNA | scientific programming | linear algebra | model builder | cli tools

Online presence

ORCID | LinkedIn | Bibliography - Published Work | CV