SEEK-VFI: Spectral Ensembling of topic models with Eigenscore for K-Agnostic Variable Feature Identification

Purpose of SEEK-VFI

This package implements the method presented in the paper "Trajectory-informed gene feature selection in single-cell analysis with SEEK-VFI" (bioRxiv).

SEEK-VFI is an ensemble machine learning method for identifying trajectory-relevant genes from gene expression count data.

Getting started

To install the R package 'seekvfi', enter the following commands in R:

install.packages("devtools")

library(devtools)

install_github("rdanning/seekvfi")

For a quick guide to using seekvec in R, please see the Tutorial.