g-quad
November 2, 2013 ยท View on GitHub
Calculates the G-quadraplex score for a FASTA file of sequences. This works by identifying all non-overlapping G-quadraplexes in a sequence and scoring them as described in: http://nar.oxfordjournals.org/content/early/2013/10/10/nar.gkt904.full.
A note: 50 nt up and downstream of putative G-quadraplexes are added to the G-quadraplex before calculating to G-score to place the G-quadraplex into context. If that runs off the end of the sequence then the G-quadraplex is discarded.
Usage
python g-quad.py your_sequences.fa